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Histologic reactions in livers of uninfected and infected wild-type BALB/c mice 9 days after a single injection of 0.25 mg of anti-CD40 MAb. Tissue response in uninfected mice (A and C) is modest compared to the pronounced reaction in infected mice (B and D) which were injected on day 12 as described in the legend to Fig. 6. Panels A and B, magnification of ×45; panels C and D, magnification of ×180.
