Table 2.

Culture of A. fumigatus from Lung Tissue after Intratracheal Administration of Conidia to X-CGD and Wild-type Mice^*

Conidia dose		Duration of study (days after conidia challenge)		Wild-type mice				X-CGD mice
				Mean cfu‡/lung		Range		Mean cfu‡/lung		Range
100,000		3–4		35		0–128 (n = 6)		22,000		2,000–40,000 (n = 4)
7,000		3–9		Not done				8,500		400–16,000 (n = 5)
1,000		7–11		100		0–200 (n = 2)		3,800		200–12,000 (n = 8)
540		8–11		0		n/a (n = 3)		870		60–4,000 (n = 5)
48		4–21		Not done				225		0–680 (n = 5)

^* Lungs were homogenized in 1 ml PBS per lung and serial dilutions were plated on Sabouraud's media in triplicate. Colonies were counted from plates containing 10–50 colonies.  

^‡cfu detected by plate culture.