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. 1997 Jan 20;185(2):239–250. doi: 10.1084/jem.185.2.239

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The total number of hybridomas expressing BP2 (B29 promoter-driven) and CPM (enlarged leader intron) hybrid loci with a given number of V_H somatic mutations. Values for wild-type 36-65V_H hybrid loci were obtained from previously published data (18). All hybridomas from CPM transgenic mice and wild-type 36-65V_H transgenic mice were generated using the hyperimmunized primary protocol and 8–10-wk-old mice. For BP2 mice, primary, secondary, and tertiary immunization protocols were used (see Materials and Methods). Those hybrid locus expressing hybridomas from the B29 line that had the largest number of mutations (>2) were from secondary and tertiary immunizations.