Table 1.

Summary of in vivo and in vitro replication profiles of SIV variants.

Virus Type	Name	Plasma Viral Load#		In vitro Replication Capacity					References
		Peak	Set-point	PHA-Stimulated Lymphoblasts	Macrophages	Dendritic Cells	Resting CD4+ T Cells	DC-T Cell Co-cultures
Early	SIVmneCl8	1.4 × 107	2.4 × 103	Low	Moderate	ND*	ND	Low	Kimata et al., 2004; Kimata and Overbaugh, 1997; Patel et al., 2002; Rudensey et al., 1995
Late (blood)	SIVmne170	5.3 × 107	6.0 × 106	High	Low	ND	ND	Low	Kimata et al., 1999; Kimata et al., 2004; Kimata and Overbaugh, 1997; Patel et al., 2002; Rudensey et al., 1995
Late (lymph node)	SIVmne027	4.2 × 108	8.3 × 106	High	Low	ND	Low	High	Kimata et al., 1998; Kimata et al., 1999; Patel et al., 2002

^#RNA copies per mL. Peak viral load for SIVmne170 is delayed by 2-3 weeks.

^*ND, not detected