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. 1997 Feb 17;185(4):583–600. doi: 10.1084/jem.185.4.583

Figure 1.

Figure 1

Figure 1

Thymic architecture of MBP-specific TCR transgenic mice and a normal nontransgenic littermate, as illustrated by ERTR5, an antibody that is specific for medullary epithelium. (A) Thymus from a MBPspecific TCR transgenic. (B) Thymus from a nontransgenic littermate. Thymi were from the MBP-specific TCR transgenic line that has a CD4/ CD8 ratio of ∼5:1 and a less pronounced thymic defect than the line with the higher CD4/CD8 ratio. Mice were (PL/J × B10.PL)F1. c, cortex; m, medulla.