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Phenotypic Characterization of BM Cells in 5′λ5 hu-CD25 Transgenic Mice and Normal Littermates
| Phenotypic markers | tg+ | tg− | ||
|---|---|---|---|---|
| (percentage of nucleated BM cells) | ||||
| B220+CD19− | 3.6 | 4.0 | ||
| CD19+ c-kit+ | 3.4 | 3.3 | ||
| CD19+ mCD25+ large | 5.2 | 4.9 | ||
| CD19+ mCD25+ small | 20.7 | 22.3 | ||
| IgM+IgD− | 10.9 | 9.7 | ||
| IgM+IgD+ | 6.1 | 5.3 | ||
The data are average values of three 6-wk-old mice each. BM cellularity was normal in all mice (1.2–1.5 × 107 cells/femur).
