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. 1997 Mar 3;185(5):933–940. doi: 10.1084/jem.185.5.933

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Protection from permanent MCA occlusion–mediated infarct in NSE-M17Z (black) compared to wild-type (white) mice. (A) Neurological grading 30 min and 24 h after occlusion. Neurological grading: 0, no neurological deficits; 1, failure to extend the right forepaw; 2, circling to the contralateral side; 3, loss of walking or righting reflex. (B) Infarct area assessed at 24 h. (C) Regional cerebral blood flow (rCBF), and mean arterial blood pressure (MBP) of wild-type and transgenic mice during 30 min of ischemia (**, P <0.01).