Fig. 11.
Role of GSH in HGF’s anti-apoptotic effect under LD. H4IIE cells were plated under LD and treated with HGF (10 ng/ml), TNFα (15 ng/ml), BSO (200 μM) alone or together in various combinations for 24 hours. At the end of the treatment, cells were processed for measurements of apoptosis or GSH levels as described in Methods. Results are expressed as mean±s.e.m. from 5 to 9 experiments. Part A: Effects on apoptosis is shown; *p<0.005 vs. control, †p<0.01 vs. TNFα, **p<0.01 vs. BSO or TNFα, ††p<0.05 vs. BSO, HGF+TNFα, or BSO+TNFα. Part B: Effects on cell GSH is shown; *p<0.01 vs. control, †p<0.01 vs. HGF, ††p<0.05 vs. TNFα, **p<0.01 vs. control or HGF+TNFα.