Figure 3.
Epinephrine inhibits LPS-induced soluble E-selectin release. Mean (± SE) plasma concentrations of soluble E-selectin after intravenous injection of LPS (2 ng/kg, lot EC-5) at t = 0. LPS = subjects injected with LPS only (n = 6); EPI-3 = subjects infused with epinephrine (30 ng/kg/min) from t = −3 h to 6 h (n = 5); EPI-24 = subjects infused with epinephrine (30 ng/kg/min) from t = −24 h to 6 h (n = 6). EPI-3 and EPI-24 reduced LPS-induced increases in soluble E-selectin levels (P <0.05 versus LPS only).