Figure 1.
The flux of rolling leukocytes (top), leukocyte adhesion (middle), and leukocyte emigration (bottom) in untreated animals (n = 3) at baseline; sham-sensitized, sham-challenged (SS; n = 3); sham-sensitized, OVA-challenged (SO; n = 8); OVA-sensitized, sham-challenged (OS; n = 6); and OVA-sensitized and OVA-challenged (OO; n = 9) animals at 4 h after antigen challenge, and SO, OS, and OO animals at 8 h after challenge. In sham- or antigen-sensitized animals, the cremaster muscle was exteriorized after 4 or 8 h of challenge and values were obtained 30 min after exteriorization. Flux, adhesion, and emigration did not change over the 30 min experimental protocol. *P <0.05 relative to respective SO and OS values. † P <0.05 relative to OO at 4 h after challenge.