Table 1.

Sequential Measures of Peripheral Blood HIV-1 Load and CD4 Counts of Infants Studied

Patient		Age		DNA PCR		Plasma culture*		PBMC culture‡		RNA§		%CD4		Absolute CD4
VI-05		Birth		Pos		0		0		ND		50		ND
		1 mo		ND		1,562		625		2,533,526
		2 mo		ND		62		625		297,670		20		3,015
		6 mo		ND		ND		ND		ND		14		1,230
VI-06		Birth		Pos		0		25		49,000		ND		ND
		1.5 mo		Pos		12.5		25		210,000		15		1,509
		3 mo		ND		62.5		125		340,000		19		1,369
		5 mo		ND		ND		ND		1,300.000		25		1,110
VI-08		Birth		Neg		ND		0		ND		41		1,051
		20 d		Pos		63		125		ND		50		2,090
		1.5 mo		ND		ND		ND		685,169		ND		ND
		5 mo		Pos		0		1		321,712		36		2,547
		6 mo		ND		ND		ND		57,302		ND		ND
VI-11		Birth		Neg		0		0		1,353		35		1,105
		2 mo		Pos		ND		0		47,654		31		2,371
		3 mo		ND		0		0		ND		34		ND
		7 mo		ND		0		5		21,555		29		2,354

The ages at which env genes were amplified from infant viral isolates for cloning and insertion into vv are denoted in bold type.  

^* TCID₅₀/ml plasma.  

^‡ TCID₅₀/10⁶ PBMC.  

^§ RNA copies/ml plasma.