Table 3.
HIV-1 env-specific CTLp Frequencies Over Time
| CTLp (95% confidence intervals) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient | vv* | Cord blood | 2 mo | 4 mo | 6 mo | 7 mo | 12 mo | 19 mo | ||||||||
| VI-06 | vac | 34 (23–50) | 0.5 (0.03–8) | |||||||||||||
| IIIB | 13 (7–23) | 153 (118–200) | ||||||||||||||
| vvVI-06-1D | 64 (47–87) | 197 (151–257) | ||||||||||||||
| VI-05 | vac | 3 (1–10) | 65 (48–89) | |||||||||||||
| IIIB | 3 (1–9) | 219 (169–284) | ||||||||||||||
| vvVI-05-2M | 8 (4–17) | 129 (99–168) | ||||||||||||||
| vvVI-05-6M | ND | 55 (40–76) | ||||||||||||||
| VI-08 | vac | 88 (66–116) | 50 (36–70) | 19 (12–32) | ||||||||||||
| IIIB | 240 (184–311) | 50 (35–70) | 201 (154–262) | |||||||||||||
| vvVI-08-20D | 165 (127–213) | 130 (99–170) | 81 (60–108) | |||||||||||||
| vvVI-08-6M | 202 (156–261) | 80 (60–107) | 175 (135–229) | |||||||||||||
| VI-11 | vac | 8 (4–17) | 3 (1–10) | 95 (72–125) | ||||||||||||
| IIIB | 23 (14–36) | 4 (1–11) | 286 (219–373) | |||||||||||||
| vvVI-11-1M | 136 (105–177) | 42 (29–60) | 537 (403–717) | |||||||||||||
| vvVI-11-3M | 138 (107–180) | 70 (52–94) | 233 (180–303) | |||||||||||||
*
vac, vaccinia alone; IIIB, vv expressing IIIB env gp160. See Table 2 for explanation of vaccinia vectors expressing infant isolates.