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. 1997 May 19;185(10):1725–1733. doi: 10.1084/jem.185.10.1725

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DBA/1LacJ mice challenged with TCR peptide B5, after CII immunization, are significantly protected from CIA. After immunization with bovine CII, mice in each group (n = 9) were challenged with B5/IFA (□) or B4/IFA (♦) on days +10, +20, +30 (A), or days +30, +40, +50 (B) relative to primary immunization with CII/CFA. These immunizations were done as described in the legend for Fig. 2.