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. 1997 Jun 16;185(12):2111–2120. doi: 10.1084/jem.185.12.2111

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B cell/T cell organization in irradiated mice reconstituted with wild-type or LTα^−/− bone marrow. Frozen sections of spleens from the recipients of BM transfer shown in Figure 5 were analyzed by staining with anti–Thy-1.2 (blue) and anti-B220 (brown). Wild-type mice that received BM from either wild-type (A) or LTα^−/− mice (B) showed segregation of B cells and T cells within lymphoid follicles, whereas the follicles of LTα^−/− mice reconstituted with BM from either wild-type (C) or LTα^−/− mice (D) showed little or no segregation of B and T cell zones.