Figure 7.

IgG production after bone marrow transfer. Wild-type and LTα^−/− mice (3–4 mice/group) were lethally irradiated and reconstituted with wild-type or LTα^−/− as in Fig. 5. 6 wk later, they were immunized i.p. with SRBC (10⁸) and boosted 21 d later. Serum was collected 10 d after both primary and secondary immunization and anti-SRBC IgG was measured by ELISA as in Fig. 3. Results represent means ± SEM. Similar results were obtained in two additional experiments.