Table 1.

>LCMV Titers of aly/aly and aly/+ Mice Early after Infection with 10⁴ PFU LCMV-WE Intravenously

Time after infection		Spleen				Liver				Lung
		aly/aly		aly/+		aly/aly		aly/+		aly/aly		aly/+
h
12		<DL* ‡		3.7 ± 0.6*		3.2 ± 0.2		3.3 ± 0.5		<DL		<DL
24		3.7 ± 0.7*		6.6 ± 0.1*		3.5 ± 0.4		3.9 ± 0.4		<DL		<DL
48		6.0 ± 0.3*		7.8 ± 0.2*		4.3 ± 0.3		3.4 ± 0.7		4.3 ± 0.3*		3.3 ± 0.2*
96		6.6 ± 0.1		6.4 ± 0.1		5.4 ± 0.3*		4.6 ± 0.3*		5.6 ± 0.2*		4.6 ± 0.3*

Mice were infected with 10⁴ PFU LCMV-WE intravenously. At the indicated time points after infection mice were killed and virus titers were determined in different organs. Values are given as log₁₀(PFU LCMV/g organ) ± SD of 3–4 mice/experimental group.  

^*  P <0.01, significant difference of LCMV titers between aly/aly and aly/+ mice (Student's t test).  

^‡  DL, detection limit of the assay (spleen, 2.0; liver, 3.0; lung, 2.5). Representative data of one out of three comparable experiments are shown.