Table 1.
MBP–NP and –GP Mice Are Able to Generate Transgene-specific CTL Capable of Lysing MHC-matched, LCMV-infected Target Cells
| Effectors | Targets | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BALB (H-2d) | MC57 (H-2b) | |||||||||||||
| Uninf | LCMV | VV–NP | Uninf | LCMV | VV–GP | |||||||||
| MBP–NP (H-2d) | MBP–GP (H-2b) | |||||||||||||
| Line 5 TG− | <3* | 52 | 37 | Line 36 TG− | <3 | 44 | 42 | |||||||
| TG+ | <3 | 41 | 29 | TG+ | <3 | 47 | 43 | |||||||
| Line 60 TG− | <3 | 43 | 24 | Line 46 TG− | <3 | 44 | 37 | |||||||
| TG+ | <3 | 34 | 17 | TG+ | <3 | 39 | 38 | |||||||
*
Values are the percentage of chromium released from MC57 or BALB target cells, with an effector/target ratio of 50:1. The data shown are the averages of values from two mice per group.