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. 1996 Dec 1;184(6):2417–2422. doi: 10.1084/jem.184.6.2417

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Rapamycin abrogates the fatal wasting syndrome that results from TGF-β1 deficiency. Progeny of TGF-β1 +/− × +/− matings were treated with rapamycin (4 mg/kg i.p.) on postnatal day 10 and 3×/ wk thereafter. Serial weights were determined before each treatment and representative data are depicted.