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. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: Atherosclerosis. 2006 Nov 15;194(1):125–133. doi: 10.1016/j.atherosclerosis.2006.10.013

Figure 3.

Figure 3

In Situ hybridization of IL-6 mRNA in aortic cross sections. Aortic cross sections were hybridized with sense (control) and anti-sense IL-6 cRNA probes. Upper panels, Aortae from sham-infused mice probed with sense (far left) and anti-sense IL-6 probes. Two different magnifications are shown (40X and 200X). Lower panels, aortae from A-II-infused mice were hybridized as in the upper panels. Predominant IL-6 staining is in the adventitial layer (purple) with additional diffuse staining in the media and endothelium. Arrow: Endothelial IL-6 staining in region of lesion development.