Figure 2.

Sequences (+ strand only) of oligonucleotides containing the overlapping region of CL1 and CL2, and mapping of the binding site of CPF. The DR1 site is indicated by the tandem overlining arrows (labeled repeats A and B). The 9-bp CPF binding site is indicated by the underlining arrow (labeled repeat C). The wild-type (WT) sequence is shown above the mutant oligonucleotide sequences (M1–M19). Bases that are underlined are those that were mutated. + denotes the formation of a DNA-protein complex, and − the absence of such a complex. The CPF-binding site within the CYP7A gene promoter and the Ftz-F1 consensus binding site are listed at the bottom, along with a sequence comparison of the binding site from human, rat, and hamster CYP7A promoters.