Figure 2.
(A) Effect of Desferal pretreatment (100 μM, for 18 h) on modulation of IRP-1-binding activity after UVA irradiation of FEK4 cells with a dose of 250 kJ/m2. The treated samples are shown as (+). The nontreated samples are shown as (–). (B) The IRP/IRE signals (from A) were quantified and their relative intensities normalized against that of the nonirradiated control cells (without Desferal pretreatment) and then expressed as a fold increase in IRP-1-binding activity above control value as a function of time after irradiation (h). (C) The controls that were not irradiated.