Table 1.
Demographics and biochemical characteristics of the 162 paediatric renal transplant candidates included in model building
| Variable | N | Mean ± SD | Range |
|---|---|---|---|
| Body weight (kg) | 162 | 22.2 ± 15.7 | 6.9–64 |
| Height (cm) | 145 | 107.3 ± 35.5 | 61.0–176 |
| Age (years) | 162 | 6.3 ± 5.7 | 0.36–17.5 |
| Blood haemoglobin (g l−1) | 148 | 104 ± 23 | 47–154 |
| Haematocrit (%) | 148 | 31 ± 7 | 15–48 |
| Serum protein content (g l−1) | 126 | 64 ± 8 | 42–83 |
| Serum prealbumin (mg l−1) | 119 | 373 ± 92 | 179–668 |
| Serum creatinine (µmol l−1) | 145 | 592 ± 252 | 165–1669 |
| Serum aspartate aminotransferase (U l−1) | 128 | 35 ± 23 | 10–247 |
| Serum alanine aminotransferase (U l−1) | 129 | 34 ± 54 | 5–564 |
| Serum alkaline phosphatase (U l−1) | 132 | 682 ± 407 | 104–1952 |
| Total plasma triglycerides, fasting value (mmol l−1) | 133 | 2.9 ± 1.5 | 0.68–8.2 |
| Total plasma cholesterol, fasting value (mmol l−1) | 132 | 5.7 ± 1.6 | 3.1–9.8 |
| Low-density lipoprotein, fasting value (mmol l−1) | 112 | 3.3 ± 1.3 | 1.2–7.4 |
| High-density lipoprotein, fasting value (mmol l−1) | 128 | 1.1 ± 0.3 | 0.47–2.3 |
The reported values had been measured within a ± 10-day range of the ciclosporin pharmacokinetic study that was carried out before transplantation.