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. 2001 Mar 5;152(5):971–984. doi: 10.1083/jcb.152.5.971

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Cytoskeletal reorganization in fibroblasts expressing PSGAP. (A) 10T1/2 cells were transfected with the indicated constructs and stained with anti–PSGAP (green) and anti–paxillin (red) antibodies. Bar, 50 μm. (B) Schematic representation of PSGAP and PSGAP mutants. The numbers represent the amino acid residues deleted from PSGAP-m. The PH domain, rhoGAP domain, and SH3 domain are indicated. Cytoskeletal reorganization index (mean ± SEM) was determined by counting the morphologically altered PSGAP-expressing cells divided by the total number of PSGAP-expressing cells, and listed at right.