Figure 4.

S. aureus–induced caspase-3 activation results in α-fodrin cleavage and DNA fragmentation. (A) Western blot analyses demonstrating caspase-3 processing (top) and α-fodrin cleavage (bottom) in Jurkat cells that were either left untreated (control) or incubated for 4 h with the indicated dilutions of Wood 46 supernatant (SN). (B) Agarose gel electrophoretic separation of DNA extracted from Jurkat cells that were either left untreated (control) or incubated for 6 h with the indicated dilutions of Wood 46 supernatant (SN). The positions of the DNA molecular size marker are indicated on the right.