Table 2.
Patient1 | Sites of Treated Disease | Response | Duration (months)2 |
---|---|---|---|
1 | Axillary, Mesenteric, and Pelvic Lymph Nodes | PR | 29 |
2 | Subcutaneous and Skin | PR | 8 |
4 | Iliac and Inguinal Lymph Nodes, Skin | PR | 2 |
6 | Intraperitoneal Lymph Nodes, Lungs, Subcutaneous | PR | 23 |
9 | Subcutaneous and Skin | PR | 11 |
10 | Inguinal Lymph Nodes, Subcutaneous and Skin | PR | 14 |
16 | Subcutaneous | CR | 58+ |
17 | Bone, Liver, Lung, Subcutaneous | CR | 57+ |
19 | Intramuscular | PR | 13 |
21 | Lung, Subcutaneous | CR | 51+ |
25 | Lung, Subcutaneous | PR | 2 |
26 | Inguinal Lymph Nodes, Liver, Subcutaneous | PR | 8 |
28 | Axillary Lymph Nodes, Brain | PR | 4 |
30 | Axillary and Inguinal Lymph Nodes, Intramuscular, Subcutaneous | PR | 7 |
31 | Liver, Lung | CR | 41+ |
32 | Skin | CR | 40+ |
33 | Lung, Subcutaneous | PR | 2 |
34 | Intramuscular, Pelvis | PR | 3 |
Patients 2, 6, and 17 had minor (Patient 6) or mixed (Patient 2 and Patient 17) responses after a first course of treatment, and were treated with a second course of treatment consisting of ablation, cell transfer and high dose IL-2 therapy prior to achieving an objective clinic response.
Measured from treatment date to time of first recurrence. Patients 16, 17, 21, 31 and 32 had ongoing responses as of May, 2007.
Adapted from Dudley et al., 2005 (Reference 23).