Figure 1. Flow diagram describing the infection spread within a given subgroup k of a city i and the implementation of interventions.

At each time, susceptibles (S⁰) could be vaccinated (V) or not (S). The remaining susceptibles could receive prophylaxis (S^P) during a given time; if not infected at the end of prophylaxis duration they re-enter the susceptible compartment. Susceptibles receiving or not prophylaxis could use masks (S^PM and S^M respectively, with S^PM becoming S^M if not infected at the end of antiviral administration period). Once infected, individuals enter the non-infectious latent state (E or E^P if under prophylaxis). Infectious symptomatic individuals (I) could be treated (I^T) (assuming that treatment is administrated in the first day of symptoms, individuals under therapy pass directly from E to I^T compartment), isolated (I^Is) or both (I^TIs). The R compartment contains all individuals who have been ill and those of latents under prophylaxis that did not develop symptoms.