Figure 2.
RSV-specific (A) and vaccinia virus–specific (B) cytolytic responses in mice primed with recombinant vaccinia virus expressing RSV-F (VF) or RSV-G (VG) glycoprotein. Splenocytes from mice previously primed with VF or VG were stimulated in vitro with RSV-infected naive spleen cells (A) or spleen cells infected with recombinant vaccinia virus not expressing RSV antigen (B). RSV-specific and vaccinia-specific cytolytic activity of these bulk cultures against target cells uninfected or infected with indicated recombinant vaccinia virus were analyzed in a standard 51Cr assay.