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. 1997 Aug 4;186(3):413–419. doi: 10.1084/jem.186.3.413

Figure 1.

Figure 1

Figure 1

Figure 1

Figure 1

Figure 1

Sequence alignments of heavy and light chain cDNAs from patients with XP-B, XP-D, XP-V and CS-A. On the top a general map of heavy and light chain genes is shown. The individual maps below show the approximate positions of nucleotide changes compared with germline V genes. Dotted lines represent unsequenced regions. As a control, ∼300 nucleotides of the constant regions of XPD-4, XPD2-1, XPD2-2, XPV-1, XPV-2, XPV-3, CSA-1, CSA-2, and CSA-3 were sequenced; no mutations were found. *These two clones have the same V and J, but different N and D sequences.