Table 1.

NER-defective EBV-transformed B Cell Lines Analyzed for Somatic Mutation

XP-B		−/−: 31-yr-old female;		Cockayne symptoms: UV sensitivity; mutation in RNA splice site of XP-B gene
		* (GM02252A)		‡(3′ → 5′ DNA helicase; component of transcription factor TFIIH)
XP-D		−/−: 5-yr-old male;		Cockayne symptoms; neurological symptoms; UV sensitivity
		(GM03249)		(5′ → 3′ DNA helicase; component of transcription factor TFIIH)
XP-V		−/−: 9-yr-old female;		photosensitivity; Cockayne symptoms: microcephaly; growth retardation; ataxia
		(GM10902		(function unknown; involved in NER and postreplication DNA repair)
CS-A		−/−: 13-yr-old male;		Cockayne syndrome; low UV recovery
		(GM01857A)		(repair of transcriptionally active DNA; interacts with TFIIH)

^* Cell repository catalog number;  

^‡ Putative function of the gene product.