Figure 3.

Wp activation early in EBV infection. (A) Time course of Wp activation. EBV was incubated with resting B cells and Wp initiated transcription was evaluated at the designated times by RT PCR. (B) Effect of calphostin C. Resting B cells were preincubated with calphostin C (50 nM) for 2 h before EBV addition. 4 h later, transcription of Wp and the rpL32 housekeeping gene were evaluated by RT PCR.