Figure 5.
Sequence of the open reading frame and of the putative protein encoded by cDNA 668. The nucleotides are numbered starting from nucleotide 70 of the cDNA 668. The translated Alu sequences are underlined. The sequence corresponding to the peptide recognized by CTL 121 is boxed. For MACHα1 and FLICE, only the stop codon TGA and the differences in nucleotides are indicated. There are two single nucleotide differences with FLICE (This sequence data is available from EMBL/GenBank/DDBJ under accession number U58143), giving rise to two different amino acids, and a single conservative difference with MACHα1 (This sequence data is available from EMBL/GenBank/DDBJ under accession number X98172). The 5′-untranslated region of cDNA 668 is identical to that of MACHα2. Therefore, compared with the cDNA sequences of CASP-8 already described, cDNA 668 is representative of a new type of transcript.