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. 1997 Aug 29;186(5):749–756. doi: 10.1084/jem.186.5.749

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Role of C5a in neutrophil elicitation in immune complex–induced peritonitis. The reverse passive Arthus reaction was allowed to proceed for 4 h (A) or 8 h (B) in C5aR (−/−) mice (striped bars) and their wild-type littermates (black bars). Total cell numbers (data not shown) and percentage of neutrophils in the peritoneal fluid were determined as described previously (13). Ab controls (Ab control) received Ab to chicken egg albumin i.p. without i.v. injection of chicken egg albumin. Mice treated with PBS i.p. followed by i.v. chicken egg albumin served as Ag controls (Ag control). Data are represented as mean ± SEM, n = 7–8 mice *P <0.004 (A), and n = 8–11 mice *P <0.05 (B).

Role of C5a in neutrophil elicitation in immune complex–induced peritonitis. The reverse passive Arthus reaction was allowed to proceed for 4 h (A) or 8 h (B) in C5aR (−/−) mice (striped bars) and their wild-type littermates (black bars). Total cell numbers (data not shown) and percentage of neutrophils in the peritoneal fluid were determined as described previously (13). Ab controls (Ab control) received Ab to chicken egg albumin i.p. without i.v. injection of chicken egg albumin. Mice treated with PBS i.p. followed by i.v. chicken egg albumin served as Ag controls (Ag control). Data are represented as mean ± SEM, n = 7–8 mice *P <0.004 (A), and n = 8–11 mice *P <0.05 (B).