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. 1997 Aug 29;186(5):749–756. doi: 10.1084/jem.186.5.749

Figure 2.

Figure 2

C5a-dependent secretion of TNF-α. The reverse passive Arthus reaction (IC) was allowed to proceed for 4 or 8 h in C5aR (−/−) (dotted bars) mice and their wild-type littermates (black bars). TNF-α content in the peritoneal fluid was determined by a TNF-α–specific ELISA. Ab controls (Ab control) received Ab to chicken egg albumin i.p. without i.v. injection of chicken egg albumin. Mice treated with PBS i.p. followed by i.v. chicken egg albumin served as Ag controls (Ag control). Data are represented as mean ± SEM, n = 14–17 mice (4 h) and n = 7–9 mice (8 h). *P <0.025.