Figure 8.

Quantitation of decreased cell infiltration in CS ears of mice treated with anti-C5 mAb. Sections of ears, as in Fig. 4, were histologically evaluated blindly. (A) Infiltration of leukocytes was graded from one to four, where one through four are, respectively, no infiltration, slight infiltration, modest infiltration, and significant infiltration. (B) Formation of intraepidermal abscesses was graded from one to three where they are, respectively, none seen, few seen, and many seen. Numbers in parentheses denote mean ± SE of histologic scores for each portion of the figure. *P <0.02 and **P <0.002, compared to positive controls (5% PCl-immunized, PBS-injected, ear-challenged group).