Table 3.
bFGF Prevents Apoptotic Death and Partially Protects from Necrosis 24 h after Exposure to Apoptosis Inducers
| Cell treatment* | Viability | DNA fragmentation | ||
|---|---|---|---|---|
| % | % | |||
| TNF 2 ng/ml | 0 | 86 ± 6.5 | ||
| TNF + bFGF 2 ng/ml | 58 | 0 | ||
| UV light 0.06 J/cm2 | 0 | 78 ± 7.0 | ||
| UV light + bFGF 2 ng/ml | 50 | 0 |
U937 cells were pretreated 3 h with bFGF before exposure to TNF or UV light. 24 h later, viability was determined by trypan blue exclusion and DNA fragmentation was measured by release of 3H-labeled DNA fragments.