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TCR-γ and TCR-δ Rearrangements in γc − and IL-7−/− Thymi
| DNA source | Vδ4-Jδ1 | Vγ4-Jγ1 | ||
|---|---|---|---|---|
| γc + | 100.00* | 100.00 | ||
| RAG 1−/− | 2.1 | 0.4 | ||
| γc − | 108.4 | 2.66 | ||
| IL-7−/− | 114.5 | 3.79 |
Rearrangements were quantitated and expressed as percentage of rearrangements found in DNA isolated from γc + total thymocyte preparations from 4-wk-old mice (see Materials and Methods). Results are representative of two independent experiments.
