Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1997 Oct 20;186(8):1315–1322. doi: 10.1084/jem.186.8.1315

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

gp96–VSV8 complexes reconstituted in vitro elicit peptide-specific, protective immunity. Mice were immunized twice at weekly intervals with gp96–VSV8 complexes (10 μg or 25 μg liver gp96 complexed with 1–2 ng VSV8 peptide), liver gp96 alone (10 or 25 μg), VSV8 peptide alone (75 ng), or RPMI medium control. gp96–VSV8 complexes were washed extensively using a minicon 50 to remove unbound peptides. All mice were challenged intraperitoneally with 5,000 live N1 cells 1 wk after the second immunization; survival was monitored.