Figure 3.
Survival of TNFR−/− mice infected with EV. Groups of five male mice of various strains were infected with 5 × 103 PFU EV in a volume of 20 μl via the footpad. The strains of mice infected were C57BL/6 × 129 (wild-type control, ⋄; p55−/−, □; p75−/−, ○; and p55−/−p75−/−, ▵). Similar observations were made in a duplicate experiment. Morbidity is discussed in the text.