Table 2.

Th Development of Lymph Node CD4⁺ T Cells from ICSBP Mutant Mice^*

Secretion		Th1 (IL-12 + anti–IL-4)				Th2 (IL-4 + anti–IFN-γ)
		IFN-γ		IL-4		IFN-γ		IL-4
		ng/ml		ng/ml		ng/ml		ng/ml
Genotype
ICSBP+/+		225 ± 10		0		3.4		20 ± 4
ICSBP−/−		112 ± 56		0.15		3.3		83 ± 19

^* CD4⁺ T cell purification and cultures were performed as described in Materials and Methods. Data are representative of four experiments.