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. 1997 Nov 17;186(10):1781–1786. doi: 10.1084/jem.186.10.1781

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⁵¹Cr-release (top) and ¹²⁵I-DNA release (bottom) from NPP-modified EL4 target cells by ex vivo–derived influenza virus A/WSN–immune Tc from mutant or B6 mice. B6 (•), gzmA^−/− (○), gzmB^−/− (□), gzmA×B^−/− (▪), and perforin^−/− (*) mice were infected intravenously with influenza virus A/WSN and their splenocytes (pool of three mice) were tested after 6 d for cytolytic (top) and nucleolytic (bottom) activities on NPP-modified EL4 target cells. Assay times were 2 and 4 h. All values are the mean lysis of triplicate samples at the four e/t values given. SEM never exceeded 3%.