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. 1997 Dec 1;186(11):1809–1818. doi: 10.1084/jem.186.11.1809

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Intracellular Ca²⁺ mobilization induced by anti–human IgG antibodies in the EBV-B cell line C1R (a) is inhibited upon crosslinking with ILT2 (b). Similarly, the increased [Ca²⁺]_i triggered through HLA-DR by the 3.8 B1 mAb in monocytes (c) and dendritic cells (not shown) is downregulated, although to a lesser extent, when ILT2 is coligated with HLA-DR (d). HP-1F7 is an isotype-matched control antibody.

Intracellular Ca²⁺ mobilization induced by anti–human IgG antibodies in the EBV-B cell line C1R (a) is inhibited upon crosslinking with ILT2 (b). Similarly, the increased [Ca²⁺]_i triggered through HLA-DR by the 3.8 B1 mAb in monocytes (c) and dendritic cells (not shown) is downregulated, although to a lesser extent, when ILT2 is coligated with HLA-DR (d). HP-1F7 is an isotype-matched control antibody.

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