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. 1997 Dec 15;186(12):2057–2062. doi: 10.1084/jem.186.12.2057

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Islet infiltration in RIP-mOVA recipients of OT-I and OT-II cells. The following numbers of OT-I and OT-II cells were adoptively transferred into unirradiated RIP-mOVA mice. (A) 5 × 10⁶ OT-I cells; (B) 0.25 × 10⁶ OT-I cells + 2 × 10⁶ OT-II cells; (C) 1 × 10⁶ OT-I cells; (D) 10 × 10⁶ OT-II cells. Sections of the pancreas were stained 5 (A, B, and D) or 8 d (C) after adoptive transfer for CD8 (A–C) or CD4 (D). Arrows in C indicate infiltrating CD8⁺ cells.