Table 1.
Correlation between the Expression Level of Ectopic Proteins and the Severity of ZO-1 Mislocalization
| ZO-1 staining | Small ring structure | Cells expressing detectable levels of ectopic aPKCs | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Completely disappeared | Fragmentary | Complete | |||||||
| % | % | % | % | ||||||
| LacZ | 0 | 0 | 6 | 1.2 | 504 | 98.8 | 0 | ND | |
| aPKCλwt | 0 | 0 | 0 | 0 | 564 | 100 | 0 | 38.8 | |
| PKCλkn | 86 | 10.4 | 426 | 51.4 | 316 | 38.2 | 43.1 | ||
| Expression level | −/+ | 9 | 1.9 | 198 | 42.0 | 264 | 56.1 | 37 | |
| + | 24 | 10.8 | 152 | 68.5 | 46 | 20.7 | 8 | 26.8 | |
| ++ | 30 | 33.7 | 54 | 60.7 | 5 | 5.6 | 1 | 10.7 | |
| +++ | 23 | 50.0 | 22 | 47.8 | 1 | 2.1 | 0 | 5.65 | |