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Percentage of Fibers with Central Nuclei
| Mice | 5 wk | 8 wk | 10 wk |
|---|---|---|---|
| Wild-type | 2.6 | 1.3 | 2.7 |
| mdx | 33.0 | 65.6 | 70.9 |
| mdx/utr−/− | 79.0 | 78.4 | 75.3 |
| α7BX2-mdx/utr−/− | 62.1 | 71.7 | 63.9 |
Sections of hindlimb muscle from 5-, 8-, and 10-wk-old mice were stained with hematoxylin and eosin. Nuclear localization was scored in ≥1,000 fibers in each animal.
