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. 2002 Jan 21;156(2):361–376. doi: 10.1083/jcb.200103037

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Characterization of the interaction between mutants of the β1A and β1D cytoplasmic domain with filamin-A and filamin-B splice variants by yeast two-hybrid analysis. Cotransformation of yeast host strain PJ69–4A with the listed combinations of β integrin cytoplasmic domains (in pAS) and filamin (in pACT). Interaction was scored as in Fig. 2. The numbers represent the amino acid positions in β1A and β1D. The conserved NPXY motifs are underlined and the amino acids in β1D that were swapped in the different chimeras are indicated by shading. The common membrane proximal region, which is shared between β1A and β1D, is boxed.