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. Author manuscript; available in PMC: 2008 Nov 23.
Published in final edited form as: Neuroscience. 2007 Aug 28;149(4):768–778. doi: 10.1016/j.neuroscience.2007.08.025

Figure 2.

Figure 2

Increased depression of synaptic transmission in APP−/− NMJs at high-frequency stimulation. A. Representative traces showing EPP depression elicited by 20, 50, 100 and 200 Hz nerve stimulation at WT or APP−/− endplates. Scale: 5 mV/100 msec. Enlarged trace under 200 Hz recording shows the amplitude values. B and C. Ratios of EPP at 10th to first (B) or the end of train to first (C) stimulus at 20, 50, 100 and 200 Hz. N=12−14 at each frequency for both genotypes. *p<0.05; **p<0.005.