Table 1.
Subjects characteristics by weight tertile
| Variable | <113 kg (n = 67) | 113–137 kg (n = 67) | >137 kg (n = 69) | P |
|---|---|---|---|---|
| Age (years) | 46 ± 12 | 45 ± 11 | 41 ± 11 | 0.055 |
| Weight (kg) | 98 ± 11 | 124 ± 7 | 161 ± 17 | <0.001 |
| Body Mass Index (kg/m2) | 38 ± 4 | 45 ± 5 | 55 ± 7 | <0.001 |
| Waist circumference (cm) | 114 ± 10 | 129 ± 9 | 150 ± 15 | <0.001 |
| Systolic blood pressure (mm Hg) | 127 ± 14 | 135 ± 14 | 127 ± 15 | 0.002 |
| Diastolic blood pressure (mm Hg) | 71 ± 9 | 75 ± 11 | 72 ± 12 | 0.103 |
| Total cholesterol (mg/dl) | 193 ± 38 | 194 ± 37 | 188 ± 41 | 0.636 |
| Low density lipoprotein cholesterol (mg/dl) | 115 ± 32 | 112 ± 31 | 112 ± 37 | 0.883 |
| High density lipoprotein cholesterol (mg/dl) | 51 ± 12 | 50 ± 16 | 46 ± 11 | 0.058 |
| Triglycerides (mg/dl) | 134 ± 61 | 163 ± 103 | 152 ± 104 | 0.197 |
| Glucose (mg/dl) | 109 ± 37 | 113 ± 47 | 104 ± 21 | 0.428 |
| Insulin (μU/mL) | 16 ± 14 | 15 ± 12 | 21 ± 11 | 0.030 |
| HOMA-IR | 3.5 ± 3.3 | 3.9 ± 6.6 | 4.3 ± 3.0 | 0.725 |
| Heart rate (beats per minute) | 71 ± 10 | 73 ± 11 | 73 ± 13 | 0.351 |
| Creatinine (mg/dl) | 0.7 ± 0.1 | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.134 |
| Hemoglobin A1c (%) | 6.2 ± 1.1 | 6.5 ± 1.6 | 6.1 ± 1.0 | 0.283 |
| Men | 8% | 15% | 38% | <0.001 |
| Smoker | 48% | 24% | 48% | 0.011 |
| Hypertension | 36% | 48% | 48% | 0.469 |
| Diabetes mellitus | 30% | 30% | 29% | 0.993 |
| Angiotensin converting enzyme inhibitor use | 13% | 19% | 17% | 0.642 |
| HMGCo-A reductase inhibitor use | 27% | 21% | 17% | 0.400 |