Table 4.
Raw data | EC50 tesofensine (nM) | EC50 M1 (nM) | EC50 M1/EC50 tesofensine |
---|---|---|---|
M1 i.v.a | NA | 318.4 | NA |
M1 i.v.+tesofensine i.v.a | 76.2 | 309.2 | 4.1 |
M1 i.v.+tesofensine i.v. and p.o. | 81.4 | 340.8 | 4.2 |
M1 i.v. and p.o.+tesofensine i.v. and p.o. | 72.3 | 363.1 | 5.0 |
NA, not applicable.
Based on central compartment concentrations.