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. 2001 Jan 22;152(2):301–308. doi: 10.1083/jcb.152.2.301

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Quantification of F4/80-positive macrophages in quadriceps and saphenous nerves of P0^+/+ op/wt (black bars, n = 5), P0^+/+ op/op (white bars, n = 3), P0^+/− op/wt (dark gray bars, n = 9), and P0^+/− op/op mice (bright gray bars, n = 3) at the age of 6 mo. The op genotype has no influence on the number of resident macrophages in quadriceps nerves of P0^+/+ mice. In quadriceps nerves of P0^+/− op/wt mice, the number of macrophages is similarly increased, as shown in Fig. 1 C, whereas homozygosity for op prevents the increase of macrophage numbers in quadriceps nerves of the myelin mutants (P0^+/− op/op). In the nondemyelinating saphenous nerves, the number of macrophages is never increased. Bars indicate mean values ± SD. ^* P < 0.05.