Figure 3.

Role of the Nup62 complex in nuclear import. Shown are the effects of anti-Nup62 Fab fragment on (A) NLS-mediated import in NRK cells; (B) the solubilization of Nup358 and Nup153 (left) and the association of importin β with these Nups (right); and (C) the binding of importin β to GST-Nup62.